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NDA+ is the necessary molecule to provide more than 95% of the energy for the human body to maintain liveliness and youthfulness

The DNA of our cells is naturally worn out every day while the body has a corresponding self-reparation system that takes place for over 10,000 times a day.

NAD+ exists in all living cells to regulate the rate of active cells. Therefore, it is a prerequisite for assisting the DNA reparation process to do its magic for maintaining one’s vitality and sustaining our lives.

Back in 2012, researchers at University of New South Wales1 examined the NAD+ content in humans of different ages, the results showed a clear decline in NAD+ levels with age2,3. Lower NAD+ level results in mitochondrial dysfunction, glucose intolerance and cellular senescence to name just a few.

    • Aging
    • Immune Stress
    • Intense Exercise
    • Sleep Disruption
    • Overeating
    • Lifestyle Stressor

NAD+ Declines and Causes Senile Diseases
To help the process of cell activating and healthy aging, we should boost NAD+ level with Puerfons Plus Age Defense Capsules to:
  • Repair damaged cells in DNA
  • Increase cellular metabolism and inhibit stem cells from aging
  • Improve muscle endurance
  • Promote hydrogen transferal in key metabolic processes and ATP synthesis for energy production
  • Activate longevity protein Sirtuin (SIRT) to boost brain energy and delay aging
What make Puerfons Plus the best anti-aging supplement in the market?
Puerfons Plus (per capsule) Direct NAD+ Supplement
Anti-aging Ingredients
  • NMN
  • NR
  • Trans Resveratrol
  • Only NMN
  • Only NR
  • Only Niacin
  • NAD
Anti-aging Ingredients
  • NMN+NR: clinically proven effective precursor of NAD+ production
  • Only NMN/NR/Niacin: not as effective as NMN+NR
  • NAD: deceptive as you cannot take NAD directly via food or supplements to get into your cells
Purity of NMN
  • Over 99.7%
  • Uncertain
Amount of NAD+ precursor
  • 12000 mg
  • ≤ 12000mg
No side effects
  • Non-GMO raw materials
  • No additives
  • No skin flushing
  • Niacin can cause skin flushing
Supplement Design
  • Vegetarian Capsule
  • Tablet / Ordinary Capsule
Production Regulations
  • Manufactured in the USA
  • FDA certified factory
  • Inspected by NSF International
  • cGMP requirement fulfilled
  • Uncertain
Safety Certification Safety Certified with Testing On:

  • Nutritional Analysis
  • Heavy Metal content
  • Microbiology
  • Uncertain
Cost Per Day(Original Price)
  • HKD$53 (2 capsules per serving)
  • More expensive yet with smaller amount of effective anti-aging ingredients
The Most Effective Anti-aging NAD+ Precursor
Comparison of NMN in Puerfons Plus and Healthy Food

Researchers at the Washington University School of Medicine examine how much NMN is in common foods and reported the values below. Puerfons Plus Age Defense Capsule is the most realistic alternative to supplement NMN daily.

2 Capsules of Puerfons Plus (200mg of NMN per serving)
of Avocado
of broccol
of mushroom
of cabbage
of cucumber
of tomato
of beer (raw)
of shrimp
The Best Comprehensive Formulation for Age Defense
Nicotinamide Mononucleotide (NMN)

In about a week of taking NMN in the drinking water, researchers could no longer tell the difference between the tissues and muscle of a 2-year-old mouse (similar to a 70-year-old elderly) and those of a 4-month-old one (smiliar to a 25-year-old young adult). Dr. David Sinclair (2017)

Best In:
  • Stability – A more stable molecule than NR
  • Able to bring some health benefits in mice studies that NR can’t
  • Critical for the activation of sirtuin genes. Sirtuins play a key role in functions that help us to live longer – by promoting DNA repair
Niacinamide Riboside (NR)

A cellular nutrient designed to permeate the cell wall with ease and nourish the cell efficiently for boosting levels of NAD+, which is linked to potential health benefits regarding aging, brain health, heart disease risk and more.

Best In:
  • A smaller molecule than NMN for easier penetration through cell wall
  • Human clinical trials proving increased NAD+ levels by up to 2.7 times
  • More readily used by your body than other NAD+ precursors
  • FDA notified as GRAS (Generally Recognized as Safe)

Found in red grapes, berries and peanuts, resveratrol is a plant compound that promotes optimal health and longevity same as the anti-aging benefits from red wine.

Best In:
  • Absorption – get to the bloodstream with higher potential health benefits than lower quality of cis-Resveratrol
  • Activate sirtuins (longevity gense) that increase lifespan is some organism

Puerfons Plus Age Defense Anti-aging Capsules ensure supplementing the lost nutrition and vitality of individuals by enhancing the level of NAD+ in human body.

We have combined NMN and NR that are both proven effective precursor of NAD+ production. Only with adequate levels of NAD+ to ensure Sirtuins have enough energy to work properly, trans-resveratrol would play its important role of multiplying the anti-aging impacts synergistically by activating the Sirtuin genes to extent lifespan.

The revolutionary formulation promotes youthful cellular energy and metabolic activity consistent with longevity, modulates the expression of genes associated with some aspects of the aging process and more.

Healthy aging
  • Activate longevity proteins Sirtuins 1-7 to restore mitochondria to a younger level to confront and delay aging process
  • Stimulate long-lived proteins SIRT1 and SIRT3 to elongate lifespan of living cells
  • Increase cell metabolism by promoting hydrogen transfer and ATP synthesis
  • Inhibit genetic changes of stem cells from aging
Strengthen self-healing ability
  • Increase the energy flow of cells and activate cellular energy
  • Accelerate self-healing ability of cells
  • Repair damaged cells in DNA
Brain functions
  • Activate brain cells
  • Improve memory descending problem
Improve body function
  • Cardiovascular and liver health
  • Improve muscle mass and reduce muscle loss
  • Enhance immunity
Fight fatigue
  • Improve sleeping quality
  • Raise concentration level
  1. In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences – PNAS 2015
  2. Why NAD+ Declines With Age – LEAF
  3. Why NAD+ Declines during Aging: It’s Destroyed – Cell Metabolism 2016


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