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WHY DO YOU NEED TO TAKE ANTIOXIDANT SUPPLEMENT?
generate Free Radicalsthatattacks & damage cells
Nucleus
Human Cell
一 Healthy cell membrance
WHAT MAKE PUERFONS ASTAXANTHIN THE BEST ANTI-INFLAMMATORY SUPPLEMENT IN THE MARKET?
Puerfons Astaxanthin (per capsule) Other Brands (per capsule)
Effective Dosage
  • 12mg of Zanthosyn® astaxanthin
  • ≤ 4 to 12 mg
Excellent Absorption
  • 3 times better

 

  • 1/3 time of Puerfons
High Purity
  • Astaxanthin compound in high purity with natural extraction from marine algae, krill, salmon, shrimps, and lobsters

 

  • Algae & krill oil (may include many unknown marine byproducts)
Certified Safety
  • cGMP, FDA certified
  • Passed nutritional, heavy metals, microbiological testing
  • Recognized as ‘GRAS’

 

  • GMP/FDA certified
Effective Dosage

It is suggested the dosage range for astaxanthin is daily. Each Purefons Astaxanthin capsule contains 12mg of Zanthosyn® astaxanthin.

Excellent Absorption

In a human study comparing Purefons Astaxanthin to a leading natural astaxanthin product, astaxanthin absorbed in the blood levels following Puerfons’ capsule were nearly 3 times higher than the other astaxanthin product at the same dose of 24 mg. This means that two 12 mg of Puerfons capsules deliver nearly the same amount of astaxanthin to the blood stream as six 12 mg capsules of other brands’ astaxanthin. And research studies suggest that higher blood levels of astaxanthin may provide greater health benefits.

High Purity

Contains pure astaxanthin prepared by natural product total synthesis. In contrast, the astaxanthin extracted from algae and krill oil is obtained in a complex mixture, which may include many unknown marine byproducts. The precision of synthetic manufacturing also provides healthcare professionals and health-conscious consumers with confidence in the quality and consistency of dosing from every capsule.

Safety

Manufactured in accordance with cGMP regulations. The form of astaxanthin utilized in Puerfons is also Generally Recognized as Safe (GRAS) according to FDA regulations.
Astaxanthin has been extensively used in animal and human health and has been present in our food chain for thousands of years. The safety of astaxanthin has been well established through the FDA’s process for determining the acceptable daily intake of dietary supplements.

HOW IS PUERFONS ASTAXANTHIN GOOD FOR YOUR HEALTH?
Comparison of the Antioxidant Effects of Astaxanthin1
800
times more than Coenzyme Q10
550
times more than Tea Polyphenols
500
times more than Vitamin E
100
times more than Lycopene
65
times more than Vitamin C
54
times more than β-carotene
6 Benefits Brought By Puerfons
Over 50 clinical and experimental studies and more than 1500 scientific articles supports the benefits of this new generation of natural yet most powerful antioxidant:
Support cardiovascular health
  • Reduce triglycerides (mainly constituted of natural fats and oils)
  • Normalize lipid profiles while boosting beneficial, good HDL-cholesterol2,3 to lower the risk of heart disease
  • Improves the stability of blood vessel structure by decreasing macrophage infiltration and apoptosis.4
  • Boosts mitochondrial energy delivery, which helps the heart muscle contract more efficiently to enhance capillary blood flow.5
Relieve joint discomfort
  • Prevent inflammation-induced illness or pain
  • Inhibit chronic inflammation
  • Reduce rheumatoid arthritis pain
  • Improve connective tissues
  • Enhance muscle endurance and resilience
Slow Brain Aging
  • Protect brain tissue17
  • Improve cognitive test battery (assess key cognitive abilities including attention, concentration, verbal learning and memory, verbal fluency, working memory and executive function) and Groton Maze Learning Test (GMLT) score in healthy middle-aged and elderly subjects with age-related forgetfulness.6,7
Strengthen the immune system
  • Protect innate immune system by increasing the numbers and activity of white blood cells and natural killer cells against invaders8,9,10
  • Prevent diseases caused by inflammation (overactive immune responses)11
Relieve eye fatigue & sour
  • Alleviate the tension of eyes’ ciliary muscles
  • Protects retinal cells against damages caused by oxidative stress12,13
  • Reduces the area of destructive new blood vessel growth on retinas14,15
Radiance skin from within
  • Protect your skin from oxidation damage for a brighter complexion16,17,18
  • Inhibit free radical that trigger skin sagging and wrinkles to increase skin elasticity19,20,21,22
Citation
  1. Nishida Y., Yamashita E., Miki W. (2007). Quenching activities of common hydrophilic and lipophilic antioxidants against singlet oxygen using chemiluminescence detection system. Carotenoid Science, 11,16–20.
  2. Yoshida H, Yanai H, Ito K, et al. Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia. Atherosclerosis. 2010 Apr;209(2):520-3.
  3. Yang Y, Seo JM, Nguyen A, et al. Astaxanthin-rich extract from the green alga Haematococcus pluvialis lowers plasma lipid concentrations and enhances antioxidant defense in apolipoprotein E knockout mice. J Nutr. 2011 Sep;141(9):1611-7.
  4. Li W, Hellsten A, Jacobsson LS, Blomqvist HM, Olsson AG, Yuan XM. Alpha-tocopherol and astaxanthin decrease macrophage infiltration, apoptosis and vulnerability in atheroma of hyperlipidaemic rabbits. J Mol Cell Cardiol. 2004 Nov;37(5):969-78.
  5. Nakao R, Nelson OL, Park JS, Mathison BD, Thompson PA, Chew BP. Effect of astaxanthin supplementation on inflammation and cardiac function in BALB/c mice. Anticancer Res. 2010 Jul;30(7):2721-5.
  6. Satoh A, Tsuji S, Okada Y, et al. Preliminary clinical evaluation of toxicity and efficacy of a new astaxanthin-rich Haematococcus pluvialis extract. J Clin Biochem Nutr. 2009 May;44(3):280-4.
  7. Katagiri M, Satoh A, Tsuji S, Shirasawa T. Effects of astaxanthin-rich Haematococcus pluvialis extract on cognitive function: a randomised, double-blind, placebo-controlled study. J Clin Biochem Nutr. 2012 Sep;51(2):102-7.
  8. Nakao R, Nelson OL, Park JS, Mathison BD, Thompson PA, Chew BP. Effect of dietary astaxanthin at different stages of mammary tumor initiation in BALB/c mice. Anticancer Res. 2010 Jun;30(6):2171-5.
  9. Chew BP, Mathison BD, Hayek MG, Massimino S, Reinhart GA, Park JS. Dietary astaxanthin enhances immune response in dogs. Vet Immunol Immunopathol. 2011 Apr 15;140(3-4):199-206.
  10. Park JS, Mathison BD, Hayek MG, Massimino S, Reinhart GA, Chew BP. Astaxanthin stimulates cell-mediated and humoral immune responses in cats. Vet Immunol Immunopathol. 2011 Dec 15;144(3-4):455-61.
  11. Chew BP, Park JS. Carotenoid action on the immune response. J Nutr. 2004 Jan;134(1):257S-61S.
  12. Izumi-Nagai K, Nagai N, Ohgami K, et al. Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin. Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1679-85.
  13. Nakajima Y, Inokuchi Y, Shimazawa M, Otsubo K, Ishibashi T, Hara H. Astaxanthin, a dietary carotenoid, protects retinal cells against oxidative stress in-vitro and in mice in-vivo. J Pharm Pharmacol. 2008 Oct;60(10):1365-74.
  14. Izumi-Nagai K, Nagai N, Ohgami K, et al. Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin. Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1679-85.
  15. Nakajima Y, Inokuchi Y, Shimazawa M, Otsubo K, Ishibashi T, Hara H. Astaxanthin, a dietary carotenoid, protects retinal cells against oxidative stress in-vitro and in mice in-vivo. J Pharm Pharmacol. 2008 Oct;60(10):1365-74.
  16. Lyons NM, O’Brien NM. Modulatory effects of an algal extract containing astaxanthin on UVA-irradiated cells in culture. J Dermatol Sci. 2002 Oct;30(1):73-84.
  17. Terazawa S, Nakajima H, Shingo M, Niwano T, Imokawa G. Astaxanthin attenuates the UVB-induced secretion of prostaglandin E2 and interleukin-8 in human keratinocytes by interrupting MSK1 phosphorylation in a ROS depletion- independent manner. Exp Dermatol. 2012 Jul;21 Suppl 1:11-7.
  18. Anunciato TP, da Rocha Filho PA. Carotenoids and polyphenols in nutricosmetics, nutraceuticals, and cosmeceuticals. J Cosmet Dermatol. 2012 Mar;11(1):51-4.
  19. Lyons NM, O’Brien NM. Modulatory effects of an algal extract containing astaxanthin on UVA-irradiated cells in culture. J Dermatol Sci. 2002 Oct;30(1):73-84.
  20. Kidd P. Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential. Altern Med Rev. 2011 Dec;16(4):355-64
  21. Martinez A, Rodriguez-Girones MA, Barbosa A, Costas M. Donator acceptor map for carotenoids, melatonin and vitamins. J Phys Chem A. 2008 Sep 25;112(38):9037-42.
  22. Suganuma K, Nakajima H, Ohtsuki M, Imokawa G. Astaxanthin attenuates the UVA-induced up-regulation of matrix- metalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts. J Dermatol Sci. 2010 May;58(2):136-42.

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