Nicotinamide Riboside(NR)

Nicotinamide Riboside

What is Nicotinamide Riboside (NR)?

Nicotinamide Riboside (NR) is a cellular nutrient designed to permeate the cell wall with ease and nourish the cell efficiently for boosting levels of NAD+, which is linked to potential health benefits regarding aging, brain health, heart disease risk and more. To work synergistically with NMN, they are both clinically proven effective precursor substance to promote the biosynthesis and production of NAD+, meaning that they serve as the “building block” to make the NAD+ molecule to delay aging.

2016 – The Effectiveness of Oral Administration of NR¹

A randomized, double-blind, three-arm crossover pharmacokinetic study in human subjects showed that NR raises NAD+ by as much as 2.7-fold in human blood with a single oral dose of 1000 mg.

2017 – Clinically Proven Effective Precursor of NAD+ Production²

Researchers at the University of Washington have completed a clinical trial with 140 participants showing that orally administered NR gives a dose dependent increase in NAD+ from 250-1000 mg/day plateauing at a 2-fold increase in NAD+ at day nine.

The blue line shows a linear regression of the change in NAD+ given the change in NR, and the shaded area shows the 95% confidence interval of that regression. .

How does Nicotinamide Riboside (NR) work?

Nicotinamide Riboside (NR) is more effective to increase NAD+ levels in your body than supplementing with straight NAD+ itself as NR can enter the cell directly without requiring a breakdown and therefore less nutrients are loss in the transferal process.

	Nicotinamide Riboside (NR) Supplement	Direct NAD+ Supplement
Mass	A cellular nutrient designed to permeate the cell wall with ease efficiently	A very large molecule that is unable to enter the cell directly
Penetration to the cells	Enter the cell directly without requiring a breakdown	Require break down to smaller pieces before passing through the cell membrane
Efficacy	Clinically proven effective in raising NAD+ level	The breakdown makes the process less efficient at increasing NAD+ in the cells
Storage in Capsule Form	Ordinary storage condition	Degrade quickly when exposed to normal light and heat

What are the benefits of taking Nicotinamide Riboside (NR)?

2017 – Positive Effects on Vascular Functions and More³

Researchers have reported positive effects of NR on vascular endothelial function in healthy middle-aged and older adults, with multiple other studies are now underway assessing the effects of NR on muscle mitochondrial function, cognition, immune function, kidney function, traumatic brain injury, brown fat activity, lipid accumulation, energy metabolism, cardiovascular risk, body composition, and acetylcarnitine levels to come.

2018-2019 – Benefits of NR on Various Aspects

A paper on Cell Metabolism co-written by Prof. Shin-ichiro Imai of Washington University School of Medicine outlined some of these benefits, including modest increases in life span, as well as slowed Alzheimer’s progress, protection against diabetes complications, improved muscle endurance, and improved heart, liver and kidney health.

從哪裡可以獲得煙酰胺核糖(NR)？

Best
Seller

Puerfons Plus Age Defense

售價 $1980

產品詳細

PUERFONS升級版
抗衰老膠囊

售價 $1980

產品詳細

	Nicotinamide Riboside (NR) supports:
	Increase the NAD+ level in the body
	Stimulate long-lived proteins SIRT1 and SIRT3 that elongate lifespan of important cells
	Balance out cell fermentation and apoptosis
	Repair damaged DNA
	Generate more cell energy
	Promote hydrogen transfer and ATP synthesis in boosting key metabolic processes
	Resist inflammatory stress and mitochondrial activities

SUBSCRIPTION