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David Sinclair- NMN, Resveretrol & Sirtuins – Is He Reversing Aging
By | June 28th, 2017 | Health Hub

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Dr. Brewer started as an Emergency Doctor. After seeing too many preventable heart attacks, he went to Johns Hopkins to learn Preventive Medicine. While there, he went on the run the post-graduate training program (residency) in Preventive Medicine. From there, he made a career of practicing and managing preventive medicine and primary care clinics. His later role in this area was Chief Medical Officer for Premise, which has close to 1,000 primary care/prevention clinics. He was also the Chief Medical Officer for MDLIVE, the second largest telemedicine company. More recently, he founded PrevMed, a heart attack, and stroke prevention clinic.

At PrevMed, we focus on heart attack, stroke, and cognitive decline. We serve patients who have already experienced an event as well as those who have not developed a diagnosis or event. Dr. Brewer provides services via telemedicine or in person if you’re in the Lexington, KY area. We find a lot of undiagnosed Pre-Diabetes or Insulin Resistance. Treating unrecognized risk factors like Pre-Diabetes allows reduction of risk and prevention of disease.

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David Sinclair, PhD, tenured faculty at Harvard, is one of the top 4 anti-aging researchers in the world. He discovered resveretrol in 2002, which stimulates SIRT2, an anti-aging genes. We haven’t heard much about resveretrol recently because you just can’t get enough. It would take 100 glasses/day of red wine to accomplish the goal.
Resveretrol stimulates SIRTs. Dr. Sinclair’s team has discovered a new booster/precursor called NMN. Clinical trials are expected within 6 months on this new anti-aging drug.
So, to review, there is a lot of research going on in anti-aging. All of it appears to be focused on cellular respiration – our individual cells and how they get energy. Valter Longo’s impacting inflammation and cell respiration by regrowing beta cells of the pancreas through intermittent fasting. Nir Barzilai’s researching anti-aging, again through impacting glucose metabolism with metformin. And in this video we discussed David Sinclair. His team has discovered a new analogue of resveretrol, NMN. NMN is a precursor/booster of NAD, another key component of the animal cell’s respiration, or metabolism.


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